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Figure 2.
Structures of BPG-1A, BPG-1B and BPG-2. (A–C) Dpo4 is
represented as a molecular surface with the polymerase core in
cyan and the LF domain in purple; DNA and nucleotide are shown
as sticks, and BP–dG is highlighted in orange. BPG-1B and
BPG-2 in B and C are rotated 180° relative to BPG-1A in A
around the DNA helix axis, to show the extrahelical BP–dG in
the gap between the core and LF domains. (D–F) The DNA
conformations corresponding to (A–C) as stick models, all with
the same orientations as in A. The primer strands are in gray,
and incoming dATP is in pink. The single-stranded portion of the
template DNA is not shown. Figs. 2, 3, and 4 were generated by
using PYMOL (46).
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