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Figure 2.
Figure 2: Homophilic dimers observed in the crystal lattice.
a, b, Ribbon diagram of the dimer in Dscam D1–D4[1.34] (a) and
Dscam D1–D4[9.9 ](b). D1 and D4, green; D2 and D3, blue for
monomer A; D1 and D4, yellow; D2 and D3, cyan for monomer B.
Residues at symmetry centre are underlined. The isoform-specific
interaction elements are shown as red and orange in molecules A
and B, respectively, and are displayed in more detail along
their respective twofold axes: c, the D2^A–D2^B interface of
Dscam D1–D4[1.34]; d, the D2^A–D2^B interface of Dscam
D1–D4[9.9] (blue and cyan residues are constant); e, the
D3^A–D3^B interface of Dscam D1–D4[1.34]; f, the D3^A–D3^B
interface of Dscam D1–D4[9.9]. Residues involved in
dimer-sustaining hydrogen bonds are labelled and the dyad axes
are displayed as black ellipsoids. The figure was prepared using
PyMOL (http://www.pymol.org).
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