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Figure 2.
Figure 2. Structural alignment of Flavivirus helicase domain
of KUNV, DENV and YFV. The conserved motifs among superfamily 2
helicases are boxed in pink (motif I, corresponding to Walker
A), cyan (motif II, corresponding to Walker B), and gray (motif
Ia, III, IV, V and VI). The different constructs are identified
above the sequences, for KUNV (in black), and below for YFV (in
yellow), respectively. The secondary structure elements
stretches indicated refer to KUNV NS3:186–619 chain A: blue,
domain I; red, domain II; and green, domain III. In dark green
is the alignment of HCV with KUNV showing the only homologues
amino acids.
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