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Figure 2.
Figure 2. Structure of the NFκB:IRF-7:IRF-3:DNA Complex
Ribbons representation of the complex viewed (A) normal to and
(B) along the DNA helical axis. The RHR of p50 is in light blue,
and that of RelA in dark blue. IRF-7D is in yellow, and IRF-3C
in green. The two DNA strands are in gray. (C) Sequence of the
DNA duplex corresponding to the PRDI-II region of the IFN-β
enhancer (−85 to −51 nucleotides from the start site of
transcription). (D) Protein-DNA contacts of IRF-3C. (E)
Protein-DNA contacts of IRF-7D.
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