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Figure 2.
Figure 2. Structure of human calcineurin in complex with
14mer PVIVIT peptide. (a) Ribbon diagram of PVIVIT (red)
sandwiched between two calcineurin heterodimers in the
asymmetric unit. CNA molecule A is colored light blue, and its
associated CNB, light green. CNA molecule C is colored dark
blue, and its associated CNB, purple. (b) Backbone hydrogen
bonds connecting PVIVIT peptide to β-sheets of the two CNA
molecules. (c) Schematic diagram of (b) depicting the position
and register of the peptide with respect to β-strands 14 of the
two CNA molecules. Residues numbered in boldface project toward
the viewer.
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