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Figure 2.
Overall structure of the SP domain of PPAF-I, shown in
standard orientation (32). A, a ribbon representation of the
PPAF-I SP domain structure. The SP domain is shown in cyan,
except for several loop regions whose color scheme is as
described in the legend to Fig. 1. Bound calcium ion is in
green, and the three disulfide bonds are drawn with sulfur atoms
in yellow. The catalytic triad residues (Ser-His-Asp) are shown
in the ball-and-stick representation. Asn-131 (c36) in 30-loop
is N-linked glycosylated. B, left, the superimposed Cα traces
of the PPAF-I SP domain (cyan) and chymotrypsinogen (orange; PDB
code 1CGI). Right, the superimposed Cα traces of the PPAF-I SP
domain (cyan) and PPAF-II SP domain (gray; PDB code 2B9L).
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