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Figure 2.
FIGURE 2. Cartoon representations of adenovirus fiber heads
in complex with CAR D1. HAd12, HAd37, and CAV-2 fiber heads are
colored blue, pink, and yellow, respectively. CAR D1 is in
green. A, top view of the structure of HAd12 fiber head in
complex with CAR D1 (13). B, as A, but HAd37 fiber head. C, as A
and B, but CAV-2 fiber head. D, part of the binding interface
between HAd12 fiber head and CAR D1 showing some key interacting
residues. E, equivalent region of interface between HAd37 fiber
head and CAR D1 showing conservation of the interactions and
additional unique interactions provided by HAd37 Glu^351 from
the IJ loop. F, same region of the CAV-2 fiber head and CAR D1
interface showing equivalent interactions made by sometimes
different fiber residues. Hydrogen bonds are shown in dotted
lines. Residues marked with an asterisk are not fully
represented for clarity.
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