Figure 2 - full size

 

Figure 2.
FIGURE 2. Unique functional domains of herpes simplex 1 DNA polymerase. A, a ribbon diagram of the pre-NH[2]-terminal domain in cyan, with electrostatic surface representation of the putative single-stranded DNA binding groove. For clarity, only surfaces from NH[2]-terminal and exonuclease domains are shown. The DNA duplex is modeled. B, ribbon diagram of the NH[2]-terminal domain embedded in the electrostatic surface representation to show the putative RNA binding cleft. The motif is on the left.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2006, 281, 18193-18200) copyright 2006.