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Figure 2.
Figure 2 Interactions of CaM with CyaA -ACD. (A) Detailed
interactions of C-CaM with four discrete regions of CyaA -ACD.
C-CaM is colored red and N-CaM is colored in orange. The
C-CaM-contact regions, helix F, helices H/H', and the C-terminal
tail of CyaA -ACD are colored green, purple, and cyan,
respectively. The atoms carbon, oxygen, nitrogen, and sulfur are
colored in gray, red, blue, and green, respectively. (B) The
interactions of CaM with EF for the comparison. The
corresponding CaM contact regions of EF, helix F, and helix H at
switch A are colored green and purple, respectively. The two
additional CaM contact regions, switch C and the helical domain,
are colored cyan and yellow, respectively. (C) Schematic diagram
showing the major contact between C-CaM with the helix H of CyaA
-ACD and EF. The CaM residues within 4 Å distance of the
indicated residues of CyaA -ACD are boxed.
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