Figure 2 - full size

 

Figure 2.
Figure 2. Comparison between the AXH Domains of ATX1 and HBP1
(A) Structure of the dimer of dimers of ATX1 as observed in the crystal structure (PDB identifier 1oa8). The subunits (A–D from left to right) are alternatively indicated with dark and light tones of green. Red circles indicate the intermolecular interfaces between each monomer in the dimer and between the two asymmetric dimers. They include the N terminus and helix α[1], respectively.
(B) Structures of subunits A and B of the AXH from ATX1.
(C) Structure of HBP1_AXH (left) and superposition of the A subunit of ATX1 AXH and HBP1_AXH (right). Only the structurally similar regions are displayed. The positions of the N and C termini and of the secondary structure elements are indicated. Figure 2. Comparison between the AXH Domains of ATX1 and HBP1(A) Structure of the dimer of dimers of ATX1 as observed in the crystal structure (PDB identifier 1oa8). The subunits (A–D from left to right) are alternatively indicated with dark and light tones of green. Red circles indicate the intermolecular interfaces between each monomer in the dimer and between the two asymmetric dimers. They include the N terminus and helix α[1], respectively.(B) Structures of subunits A and B of the AXH from ATX1.(C) Structure of HBP1_AXH (left) and superposition of the A subunit of ATX1 AXH and HBP1_AXH (right). Only the structurally similar regions are displayed. The positions of the N and C termini and of the secondary structure elements are indicated.

The above figure is reprinted by permission from Cell Press: Structure (2005, 13, 743-753) copyright 2005.