Figure 2.
Figure 2 Structures of N-CaM and its interaction with EF. (A)
Structures of N-CaM (red) in EF -CaM complex at 1 M
calcium, 1 mM calcium, 10 mM calcium concentrations in
comparison with the calcium-free N-CaM structure (left, PDB
code: 1CFD) and the crystal structure of four calcium-loaded CaM
(right, PDB code: 1CLL). Calcium ions are colored in orange. (B)
The interaction between N-CaM and the helical domain of EF. The
helical domains of EF and N-CaM of the EF -CaM complex at 10 mM
calcium concentration are colored in yellow and red,
respectively. For comparison, four calcium-loaded CaM is shown
in cyan. (C) Detailed hydrogen bonding and salt bridge formed at
the interface between helices I and II of N-CaM and helices L
and M of EF.
The above figure is reprinted
from an Open Access publication published by Macmillan Publishers Ltd:
EMBO J
(2005,
24,
929-941)
copyright 2005.
M
calcium, 1 mM calcium, 10 mM calcium concentrations in
comparison with the calcium-free N-CaM structure (left, PDB
code: 1CFD) and the crystal structure of four calcium-loaded CaM
(right, PDB code: 1CLL). Calcium ions are colored in orange. (B)
The interaction between N-CaM and the helical domain of EF. The
helical domains of EF and N-CaM of the EF -CaM complex at 10 mM
calcium concentration are colored in yellow and red,
respectively. For comparison, four calcium-loaded CaM is shown
in cyan. (C) Detailed hydrogen bonding and salt bridge formed at
the interface between helices I and II of N-CaM and helices L
and M of EF.