Figure 2.
Figure 2. Relaxed stereo diagram ribbon drawing of the human
apo K1 structure (light grey) and the overlaid kallikrein loop
regions of horse K3 (1GVZ, magenta), porcine K1 (2PKA, red),
mouse GK3 (1SGF, blue), mouse GK13 (1AO5, green) and rat GK2
(1TON, yellow), with the human K1 kallikrein loop indicated in
dark grey. The active site His 57, Asp 102, and Ser 195 residues
in human K1, as well as the Asp 189 at the base of the S1 pocket
are indicated in wire frame representation. The location of the
S1 and S1 pockets
are indicated. The carbohydrate moiety attached to Asn 95,
observed in the human K1, mouse GK3 and mouse GK13 structures,
is also indicated in wire frame shown.
The above figure is reprinted
by permission from John Wiley & Sons, Inc.:
Proteins
(2005,
58,
802-814)
copyright 2005.
pockets
are indicated. The carbohydrate moiety attached to Asn 95,
observed in the human K1, mouse GK3 and mouse GK13 structures,
is also indicated in wire frame shown.