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Figure 2.
Figure 2. Structure of Den1-Nedd8. A, Ribbon representation
of the secondary structure of the human Den1 in complex with
Nedd8. b Strands from Den1 (yellow) and from Nedd8 (orange) are
numbered and a helices from Den1 (pink) and from Nedd8 (red) are
lettered. Den1 catalytic residues and the Nedd8 Gly-Gly motif
are numbered and shown in bond representation. N and C termini
of each polypeptide chain are labeled as N[t] or C[t],
respectively. B, The 90° rotation of the ribbon
representation shown in A. Graphics were prepared using Pymol
unless otherwise noted.51
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