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Figure 2.
Figure 2: Stereoview of the primer C74-C75 and the incoming ATP.
a,  [A]-Weighted
simulated-annealing F[o] - F[c] omit maps contoured at 3.5 around
C74-C75 and AMPcPP. The carbon atoms of Aa.LC, tRNA and AMPcPP
are coloured white, pink and blue, respectively. b, Recognition
of the incoming ATP. Ball-and-stick representations of tRNA C75,
AMPcPP and the ATP-interacting residues are shown on the Aa.LC
head and neck domains. The colouring scheme is the same as in
Fig. 1. c, Recognition of the C74-C75 terminus. Ball-and-stick
representations of tRNA A73-C74-C75, AMPcPP and the
tRNA-interacting residues are shown. Phe 106 and the Asp105
-Arg155 pair, which are part of the 'stacking arc', are also
shown in ball-and-stick representation. In b and c, hydrogen
bonds are shown as dotted lines.
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