Figure 2 - full size

 

Figure 2.
Figure 2. Oligosaccharides used in structural studies of DC-SIGN and DC-SIGNR. Symbols are as defined in Figure 1. Structures of the complexes of both proteins with the GlcNAc[2]Man[3] oligosaccharide are as described^14. This oligosaccharide contains a branch mannose that is not linked to other sugars. The branch mannose residues in the high-mannose oligosaccharide are linked in either (outer branch) or (core branch) configuration. The Man[4] oligosaccharide is an analog of the outer branch structure.

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nat Struct Mol Biol (2004, 11, 591-598) copyright 2004.