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Figure 2.
Figure 2. The Crystal Structure of the MMLV RT and a
Comparison with the p66 Subunit of the HIV-1 RT(A) A ribbon
rendering of the MMLV RT is shown with the fingers domain in
red, palm in blue, thumb in green, connection in yellow, and the
RNase H in magenta.(B) A structural comparison of the MMLV RT
monomer is shown in the same color scheme as in (A) with the p66
subunit of HIV-1 RT shown in gray. The structures were
superimposed using the highly conserved structural elements in
the palm domains. In contrast to the rather extended p66 subunit
of HIV-1 RT, the MMLV RT is a far more clamp-shaped molecule.
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