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Figure 2.
Figure 2. A, Stereo view of the selectivity filter region
for the T75C mutant KcsA channel. The structure, solved in 200
mM K+, is shown with residues E71 to D80 (from two diagonally
opposed subunits) rendered in a ball-and-stick representation.
Green spheres represent K+ binding sites in the filter, and the
magenta sphere represents a site with residual electron density.
The 2F[o] -F[c] electron density map (contoured at 2s)
validating the structure is shown as a blue mesh. B, Stereo view
of the selectivity filter region for the wild-type KcsA. The
structure (PDB code 1K4C[3.]), solved in 200 mM K+, is
represented in the same way as in A. C, Stereo view of the
selectivity filter region of the T75C (red) superimposed on that
of the wild-type (blue).
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