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Figure 2.
Figure 2. Comparison of the NNRTI-binding sites of
wild-type and mutant HIV-1 RTs. a, Leu100Ile with nevirapine. b,
Leu100Ile with TNK-651. c, Leu100Ile and UC-781. The CA
backbones and side-chains are shown as thin and thick bonds,
coloured in orange and blue for wild-type and mutant RTs,
respectively. For clarity the inhibitors and the side-chains of
the corresponding mutation sites are coloured in red for
wild-type and cyan for mutant RTs.
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