Figure 2 - full size

 

Figure 2.
Figure 2. Three-dimensional structure of the V23 -HRV2 complex. (a) Stereo view of the 3.5 Å -averaged electron density of V3 bound to HRV2. The region corresponds to residues from His13 to Glu36 of the V3 receptor. The V3 model is also shown in ball-and-stick representation. The Ca^2+ ion in the center of the acidic cluster is green. Residues involved directly in interactions with HRV2 are labeled. (b) Orthogonal views of an HRV2-V3 pentamer subunit. HRV2 proteins are shown as space-filling model colored in the standard viral protein color code (VP1, blue, VP2, green and VP3, red) in the reference protomer and light blue in the others. The five V3 receptors are shown as worms in yellow.

The above figure is reprinted by permission from Macmillan Publishers Ltd: Nat Struct Mol Biol (2004, 11, 429-434) copyright 2004.