Figure 2 - full size

 

Figure 2.
Figure 2 Protein/DNA contacts in polymerizing and editing conformations. (A) Polymerase mode. Hydrogen bond contacts less than 2.8 Å are represented by solid lines and those greater than 2.8 and less than 3.5 Å are shown with dashed lines. Residues in parentheses represent charge interactions longer than 3.5 Å. Wavy lines represent water-mediated contacts. Hydrophobic interactions are symbolized by dashed arcs. Contacts mediated by a nitrogen main-chain atom are indicated by the suffix 'N'. Protein residues are colored according to their domain location: exonuclease (cyan), N-terminal domain (orange), palm (red), thumb (green) and fingers (blue). Underlined residues are contacts in Pol1 that are absent in Pol2. (B) Exonuclease mode. All descriptions as above.

The above figure is reprinted from an Open Access publication published by Macmillan Publishers Ltd: EMBO J (2004, 23, 1483-1493) copyright 2004.