Figure 2 - full size

Figure 2. Figure 2. DNA Mismatches Bound at the Polymerase Postinsertion SiteThe bases are shown in the same orientation and location as the G•C base pair in Figure 1B. Left, hydrogen bonding pattern. Right, superimposition of the molecular surface of the mismatch (red) and cognate G•C base pair (yellow, PDB ID 1L3S) bound at the postinsertion site, highlighting differences in shape and location of the primer terminus.

The above figure is reprinted by permission from Cell Press: Cell (2004, 116, 803-816) copyright 2004.