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Figure 2.
Fig. 2. Spectral perturbation for  IIb/DPC and  3/DPC
interactions. (A) Heteronuclear single quantum correlation
(HSQC) spectra of 15N-labeled IIb in the absence
(black) and presence (red) of 300 mM DPC showing dramatic
perturbation in the membrane-proximal region K989-R997. (B) HSQC
spectra of 15N-labeled 3 in the absence (black)
and presence (red) of 300 mM DPC. A global spectral perturbation
occurs indicating a complex structural rearrangement as compared
to IIb in A.
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