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Figure 2.
Figure 2. Surface features. (a) Conservation. The
solvent-accessible surface is colored in yellow and orange at
locations for invariant and conserved residues, respectively,
according to Figure 1a. Residues that are essential for DNA
polymerase activity are labeled. The view is as in Figure 1b,
left. (b) Charge distribution. The surface is colored from
negative (red) to positive charge (blue). Residues involved in
DNA binding are labeled. The view on the right is related to
that on the left by a 20° rotation about a vertical axis. The
dashed circle shows the presumed location of the DNA duplex
emanating from the active site toward the reader.
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