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Figure 2.
Figure 2. Overall Structure of the APPBP1-UBA3-NEDD8-ATP
ComplexThree views of the complex are shown in cartoon (top) and
space-filling representations (bottom), each view a
35°–55° rotation around the y axis as indicated.
APPBP1 is shown in blue, UBA3 in red, NEDD8 in yellow, and the
position of the catalytic cysteine (C216A here) in green. The
location of ATP is indicated in each view in the cartoon
representations. The adenylation domain, the catalytic cysteine
domain, and the C-terminal domain (CTD) are indicated. Figures
were made using Pymol (DeLano, 2002).
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