Figure 2 - full size

 

Figure 2.
Figure 2. Overall Structure of the APPBP1-UBA3-NEDD8-ATP ComplexThree views of the complex are shown in cartoon (top) and space-filling representations (bottom), each view a 35°–55° rotation around the y axis as indicated. APPBP1 is shown in blue, UBA3 in red, NEDD8 in yellow, and the position of the catalytic cysteine (C216A here) in green. The location of ATP is indicated in each view in the cartoon representations. The adenylation domain, the catalytic cysteine domain, and the C-terminal domain (CTD) are indicated. Figures were made using Pymol (DeLano, 2002).

The above figure is reprinted by permission from Cell Press: Mol Cell (2003, 12, 1427-1437) copyright 2003.