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Figure 2.
FIG. 2. Quaternary structure model of the S. cerevisiae
SDH. A, ribbon representation of SDH. Sdh1p, Sdh2p, Sdh3p, and
Sdh4p are shown in gold, green, red, and blue, respectively. The
iron-sulfur clusters are shown as cyan (S atoms) and red (Fe
atoms); FAD and heme b are shown as purple; quinones are shown
in yellow. B, superposition of the S. cerevisiae SDH (blue) with
the E. coli SDH (yellow). C, structure of the flavoprotein
(Sdh1p). His-62, which is covalently linked to the FAD is shown
in red. D, the iron-sulfur protein (Sdh2p) with the three
iron-sulfur clusters.
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