Figure 2.
FIG. 2. Crystal structure of IRKD1132N. A, 2F[o] - F[c]
electron density map (1.9 Å resolution, 1 contour)
is shown in wire mesh (purple) in the region of Tyr-984. The
superimposed refined structure of IRKD1132N is shown in stick
representation, with the proximal juxtamembrane region (residues
978-988) colored orange, residues in C colored yellow, and
residues in the sheet (and connecting
loops) colored cyan. Ordered water molecules are indicated with
red spheres. Selected residues are labeled. B, ribbon diagram of
the IRKD1132N structure. strands are colored
cyan, and -helices are colored
yellow. The proximal juxtamembrane region including Tyr-984 is
colored orange, with the side chain of Tyr-984 shown in
ball-and-stick representation, and C in the N-terminal
lobe is labeled. The dashed gray line indicates that the
activation loop is disordered (from Met-1153 through Leu-1171).
The N and C termini are denoted by N and C.
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2003,
278,
26007-26014)
copyright 2003.
contour)
is shown in wire mesh (purple) in the region of Tyr-984. The
superimposed refined structure of IRKD1132N is shown in stick
representation, with the proximal juxtamembrane region (residues
978-988) colored orange, residues in 
C colored yellow, and
residues in the 
sheet (and connecting
loops) colored cyan. Ordered water molecules are indicated with
red spheres. Selected residues are labeled. B, ribbon diagram of
the IRKD1132N structure.