Figure 2.
Figure 2 Structure of the GCM domain. (A) Ribbon representation
of the GCM domain bound to its cognate DNA. The -sheets
of the large and small domains are depicted in dark blue and
light blue, respectively. Helices H1, H2 and H3 are shown in
red, and the DNA is shown in yellow. The two Zn ions and their
coordinating ligands are depicted. Figures 2A and B, 3B, 4A and
6 were produced using the program RIBBONS (Carson, 1991). (B)
View of the GCM domain with the DNA axis running vertically. DNA
bases are numbered according to Figure 1B. (C) Topology diagram
of the GCM domain. DNA-contacting residues and the first and
second Zn ion coordinating residues are marked as dots. The
color code corresponds to Figures 1A and 2A.
The above figure is reprinted
from an Open Access publication published by Macmillan Publishers Ltd:
EMBO J
(2003,
22,
1835-1845)
copyright 2003.
-sheets
of the large and small domains are depicted in dark blue and
light blue, respectively. Helices H1, H2 and H3 are shown in
red, and the DNA is shown in yellow. The two Zn ions and their
coordinating ligands are depicted. Figures 2A and B, 3B, 4A and
6 were produced using the program RIBBONS (Carson, 1991). (B)
View of the GCM domain with the DNA axis running vertically. DNA
bases are numbered according to Figure 1B. (C) Topology diagram
of the GCM domain. DNA-contacting residues and the first and
second Zn ion coordinating residues are marked as dots. The
color code corresponds to Figures 1A and 2A.