Figure 3 - full size

 

Figure 3.
Figure 3. Interactions between EGF and EGFREGF and the EGFR domains are colored in the same manner as in Figure 1, except for (B).(A) Mapping the interaction sites onto ribbon representations of EGFR and EGF. Three binding sites in the interface are outlined.(B) EGF structure. The A, B, and C loops are colored blue, green, and red, respectively. The other regions are pale green.(C) Stereo view of the interface at site 1. Only the side chains of interacting residues are shown. Dotted lines represent hydrogen bonds.(D) Stereo view of the interface at site 2.(E) Stereo view of the interface at site 3.

The above figure is reprinted by permission from Cell Press: Cell (2002, 110, 775-787) copyright 2002.