Figure 2.
Figure 2. A new allosteric binding pocket for compound 1 in
human p38 MAP kinase. a, Schematic drawing of the structure
of p38 MAP kinase in complex with compound 1. The inhibitor is
shown as a stick model, with carbon atoms in green. The expected
location of the ATP molecule^8 (purple for carbon atoms) is
shown for reference. b, Final 2F[o] - F[c] electron density map
for compound 1, contoured at 1 level.
Panel (a) is produced with RIBBONS27 and panel (b) with SETOR28.
The above figure is reprinted
by permission from Macmillan Publishers Ltd:
Nat Struct Biol
(2002,
9,
268-272)
copyright 2002.
level.
Panel (a) is produced with RIBBONS27 and panel (b) with SETOR28.