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Figure 2.
Fig. 2. The ligand-integrin binding site. (A) Surface
representation of the ligand-binding site, with the ligand
peptide shown as ball-and-stick model. Color code for the ligand
and the two visible Mn2+ ions (MIDAS and ADMIDAS) is as in Fig.
1. (B) Interactions between ligand and integrin. The peptide
(yellow) and residues interacting with the ligand or with Mn2+
ions are shown in ball-and-stick representation.  V and  3 residues
are labeled blue and red, respectively. Oxygen and nitrogen
atoms are in red and blue, respectively. The three Mn2+ ions in
3 at MIDAS,
ADMIDAS, and LIMBS are also shown. Hydrogen bonds and salt
bridges (distance cutoff, 3.5 Å) are represented with
dotted lines.
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