Figure 2.
Fig. 2. Ribbon diagrams comparing actin and the two Arps in the
Arp2/3 complex. (A) Rabbit skeletal muscle actin from the
cocrystal with DNase I (PDB accession number 1ATN). (B) Arp2.
Subdomains 3 and 4 are the refined model consisting of residues
Gly154 to Arg343. The backbone of actin subdomains 1 and 2
(shaded gray-red) is positioned according to the experimental
density of the helices
in the refined map of the Arp2/3 complex. The insert
Tyr325-Glu335 in subdomain 3 is colored green. (C) Arp3. The
major inserts (Gln46 to Cys54, Thr154 to Arg161, Asn260 to
Lys264, and Val347 to Leu358) are colored green. Residues 40 to
50 do not appear in the electron density map.
The above figure is reprinted
by permission from the AAAs:
Science
(2001,
294,
1679-1684)
copyright 2001.
helices
in the refined map of the Arp2/3 complex. The insert
Tyr325-Glu335 in subdomain 3 is colored green. (C) Arp3. The
major inserts (Gln46 to Cys54, Thr154 to Arg161, Asn260 to
Lys264, and Val347 to Leu358) are colored green. Residues 40 to
50 do not appear in the electron density map.