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Figure 2.
Figure 2. Close-up of binding site 1 in eight different
structures. C^a positions for residues 125-138 are shown, along
with side-chain atoms for residues Tyr129, Trp130, and Tyr131.
(a) Chains are colored according to the scheme in Figure 1: form
M1, white; form M2 (copy A), green; form M2 (copy B), yellow;
form H1, blue; form Complex1, cyan; form T1 (copies A and B),
red; form T2 (copy A), magenta. Other copies of the tetragonal
forms are identical; only one representative structure is shown.
In form M1, form M2A, and form H1, the coordinates differ from
canonical C' structure. (b) The same Figure is shown with a
different coloring scheme, showing the variation in location of
three aromatic residues. Side-chain atoms for Tyr129 appear red,
for Trp130 appear blue, and for Tyr131 appear yellow. Tyr131 in
form M2A falls in nearly the same location as Tyr129 in most
crystal forms.
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