Figure 2.
Figure 2: Structure of the Ku-DNA complex. a, View down the
DNA helix. Ku70 is coloured red and Ku80 orange. Only the 14-bp
duplex portion of DNA is shown; the sugar-phosphate backbone is
coloured light grey and the bases dark grey. b, Side view. Black
line indicates the molecular dyad axis. Terminal base pairs are
numbered +8 (broken DNA end) and -6. c, Abbreviated topology
diagram showing the fold of Ku70 and Ku80. Green rods indicate
-helices;
blue arrows indicate -strands.
d, Stereo difference electron density map viewed down the
molecular dyad axis (white symbol). Blue contour lines show
electron density at the 2.4 -level
in a |F[o]| - |F[c]| (2.5 Å resolution) map calculated after
simulated-annealing refinement of a model lacking nucleotides
from levels -2 to +6 of the 34-residue oligonucleotide.
The above figure is reprinted
by permission from Macmillan Publishers Ltd:
Nature
(2001,
412,
607-614)
copyright 2001.
-helices;
blue arrows indicate 
-strands.
d, Stereo difference electron density map viewed down the
molecular dyad axis (white symbol). Blue contour lines show
electron density at the 2.4 
-level
in a |F[o]| - |F[c]| (2.5 Å resolution) map calculated after
simulated-annealing refinement of a model lacking nucleotides
from levels -2 to +6 of the 34-residue oligonucleotide.