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Figure 2.
Fig. 2. Location of the nanolog molecule within the
active site. The orientations of the nanolog molecules compared
with ADP·BeF[x] are shown. a shows the adenine base of
ADP located in the base pocket that is formed by residues
Asn127-Tyr135. The coordinates for this figure were taken from
1MMD (17). c, the ATP nucleotide molecule is shown as ball and
stick with yellow bonds. The colors of specific atoms are as in
Fig. 1. The nanolog molecules are superimposed on the molecule
of ADP·BeF[x] and are represented in solid colors. b,
o-NPhAE, m-NPhAE, and p-NPhAE are shown in orange, cyan, and
magenta, respectively. c, o,p-DNPhAE, o,p-DNPhAP, and
N-methyl-NPhAE are shown in purple, red, and green,
respectively. The protein backbones were aligned with the
program LSQKAB implemented in the CCP4 program package (33, 41)
where all  carbons
were included in the calculation.
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