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Figure 2.
Fig. 2. The E6AP catalytic cysteine (Cys820) maps to the
interface between the N and C lobes of the hect domain. Residues
of the active-site loop and those that make N-C lobe contacts
are shown in yellow. N and C lobes are colored red and green,
respectively. The hinge region (residues 738 to 740) between the
N and C lobes is colored white. White dashed lines indicate
hydrogen bonds; red atoms, oxygen; blue, nitrogen; green,
sulfur.
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