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Figure 2.
Figure 2. Specific Interactions of Rho13N with Its Target
RNA(a) The RNA moiety (blue sticks) is shown on a surface
representation of the Rho13N C-terminal subdomain. The C[α]
path of Rho13N is marked by a gold coil, while residues and
atoms that interact directly with the RNA are colored black and
labeled.(b) Stereo view of the environment around the first RNA
cytosine. A Van der Waals dot surface is drawn about the protein
atoms. Hydrogen bonds are indicated by dashed lines.(c) Stereo
view of the Watson/Crick-like recognition of the hydrogen bond
donor/acceptor groups of the second RNA cytosine by Arg-66 and
Asp-78; the cytidine base stacks on the ring of Phe-64. The
orientation of these side chains with respect to the cytosine
base is tilted slightly, analogous to a “propeller
twist.”(d) Stereo view of a DNA C·G base pair (from PDB
accession number 126D [[29]]); the cytosine base is stacked on
the ring of a second cytosine (figure generated by RIBBONS [
[12]]).
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