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Figure 2.
Figure 2. Comparison of Human CD94 and Rat MBP-ACD94 is
magenta and MBP-A (Brookhaven PDB entry 1RTM) is blue.(A) Loops
3 and 6 in CD94. Side chains displayed are those that play a
prominent role in stabilizing loop 3. Acidic residues are red,
basic residues are blue, and neutral residues are tan. Two salt
bridges are designated by dotted lines.(B) Superposition of the
Ca^2+-binding site of rat MBP-A with the same region in the
human CD94 structure (loop 5 and β strand 6). Ca^2+-binding
residues from MBP-A and potential Ca^2+-binding residues in CD94
are represented by ball-and-stick models.(C) Superimposed and
separated ribbon diagrams of the C-type lectin domains from CD94
(left) and MBP-A (right).
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