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Figure 1.
Fig. 1. Cutaway diagram of an  -like DNA
polymerase active site containing primer/template and ACV-TP.
The -carbon
backbone of the protein chain derived from the structure of RB69
DNA polymerase (10) is presented as a gray ribbon diagram. The
location of the N terminus of conserved region II is indicated
with an arrow. The positions of amino acids altered by HSV drug
resistance mutations (e.g., R700G) as well as a conserved serine
(S720) relative to the RB69 sequence are indicated with black
dots and were aligned according to Wang et al. (10).
Primer/template is presented as two ribbons in the upper right
quadrant of the figure and ACV-TP is presented as gray dots
connected by gray lines.
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