Figure 1.
Figure 1. a, The Shaw T1 tetramer drawn in MOLSCRIPT^37 and
rendered using POVRAY version 3.0. The subunit to the front
is not shown for clarity. The four-fold axis is vertical down
the central cavity. Layer 1 (residues 10−56) is colored in
green; layer 2 (residues 57−71) in blue; layer 3 (residues
72−94) in red; and layer 4 (95−111) in yellow. Zinc atoms
are shown as gray spheres. b, Stereodiagram of C traces
of the superposition of the Shaw T1 (green) and Shaker T1
(magenta) structures (SETOR^ 38) in the same view as in Fig. 1a.
Secondary structure elements, N- and C- termini are labeled.
Arrows 1 and 2 denote two major variable regions between the two
structures. The vertical line represents the four-fold axis. c,
Stereodiagram of C traces
of the Shaw T1 (green) and Shaker T1 (magenta) to highlight the
difference in layer 4, viewed from the top of the teteramer in a
direction ~45^o tilted from the four-fold axis. The vertical
line in the background represents the four-fold axis.
The above figure is reprinted
by permission from Macmillan Publishers Ltd:
Nat Struct Biol
(1999,
6,
38-43)
copyright 1999.
traces
of the superposition of the Shaw T1 (green) and Shaker T1
(magenta) structures (SETOR^ 38) in the same view as in Fig. 1a.
Secondary structure elements, N- and C- termini are labeled.
Arrows 1 and 2 denote two major variable regions between the two
structures. The vertical line represents the four-fold axis. c,
Stereodiagram of C