Figure 1.
Fig. 1. RT-DNA tethering reaction. Chemistry of disulfide
bond formation between the side chain of an engineered cysteine
residue (blue) in helix H (gold) of RT to a thiol group in the
minor groove of DNA (activated as the mixed disulfide), which is
tethered to N2 of a dG (green) in the template:primer.
The above figure is reprinted
by permission from the AAAs:
Science
(1998,
282,
1669-1675)
copyright 1998.
