Figure 1 - full size

 

Figure 1.
Figure 1. Diagram of HBY 097 (a quinoxaline derivative) contacts with protein residues around the NNIBP in both (a) wild-type HIV-1 RT/HBY 097 and (b) Tyr188Leu mutant HIV-1 RT/HBY 097 complexes. Distances ( slant 3.6 Å) between protein and inhibitor atoms are indicated.

The above figure is reprinted by permission from Elsevier: J Mol Biol (1998, 284, 313-323) copyright 1998.