Figure 1.
Fig. 1. The chemical structure of the p56^lck SH2 domain
inhibitor used in the current study. The inhibitor contains a
cmF residue as a replacement for the pY residue. The cmFEEI
inhibitor is about 450-fold less potent than the pYEEI inhibitor
(pH 7.4) in the binding of the SH2 domain.
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(1998,
273,
20238-20242)
copyright 1998.
