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Figure 1.
Figure 1. Backbone Worm Diagram of Two N-Cadherin D1
Molecules and Molecular Details of the Strand Dimer
Interaction(A) Backbone worm diagram of two N-cadherin D1
molecules involved in strand dimer pairing (from the crystal
structure with Protein Data Bank accession code 1NCG). Only the
side chain from Trp-2 is shown; the N and C termini are noted,
and calcium-analog ytterbium ions are shown as pink spheres.(B)
Molecular details of the strand dimer interaction. The A strand
of one protomer is colored in green; for clarity, the rest of
this protomer is not displayed. Residues that line the Trp-2
acceptor pocket are colored in blue. Residue positions that we
have mutated in this paper are underlined in red. His-79 and
Val-81 are colored gold; they have been implicated in prior
studies as residues important for adhesion.
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