Figure 1.
Fig. 1. Orbital steering in enzyme-catalyzed reactions can
lead (A) to properly aligned substrates by maximizing bonding
orbital overlaps and minimizing anti-bonding orbital overlaps or
can lead^ (B) to improperly aligned substrates if the reaction
coordinate^ trajectory is perturbed by modification.
The above figure is reprinted
by permission from the AAAs:
Science
(1997,
277,
202-206)
copyright 1997.
