Figure 3.
Fig. 3. 2F[o] F[c]
electron density maps computed after simulated annnealing (1000
K) with the inhibitors omitted from the atomic models. Carbon
atoms are colored yellow, oxygen atoms red, and nitrogen atoms
blue. The red spheres represent water molecules. Maps are^
contoured at 1 . (A) Map
of FGFR1K-SU4984 computed at 2.4^ Å resolution. (B) Map of
FGFR1K-SU5402 computed at 2.5^ Å resolution. Figure
prepared with SETOR (34).
The above figure is reprinted
by permission from the AAAs:
Science
(1997,
276,
955-960)
copyright 1997.
F[c]
electron density maps computed after simulated annnealing (1000
K) with the inhibitors omitted from the atomic models. Carbon
atoms are colored yellow, oxygen atoms red, and nitrogen atoms
blue. The red spheres represent water molecules. Maps are^
contoured at 1 
. (A) Map
of FGFR1K-SU4984 computed at 2.4^ Å resolution. (B) Map of
FGFR1K-SU5402 computed at 2.5^ Å resolution. Figure
prepared with SETOR (34).