Figure 1.
Crystal Structures of NS3h Complexes. (A) NS3h in complex
with ssDNA (dA[6]). (B) NS3h in complex with ADP·BeF[3]
and ssDNA (dT[12], with five deoxynucleosides presented for
clarity). (C) NS3h in complex with and
ssDNA (dT[6]). The structures are represented by ribbons and
transparent surfaces. The DNA bases and deoxyribose groups are
shown with sticks and numerically labeled. The DNA
phosphodiester backbones are simplified as orange tubes. The DNA
atoms are color coded according to elements. The helicase motifs
are color coded in the surface and ribbon respectively in (B)
and (C). The distances between the Cα atoms of K244 (domain 1)
and S403 (domain 2) are noted. ADP·BeF[3] and are
shown with sticks and color coded.
and
ssDNA (dT[6]). The structures are represented by ribbons and
transparent surfaces. The DNA bases and deoxyribose groups are
shown with sticks and numerically labeled. The DNA
phosphodiester backbones are simplified as orange tubes. The DNA
atoms are color coded according to elements. The helicase motifs
are color coded in the surface and ribbon respectively in (B)
and (C). The distances between the Cα atoms of K244 (domain 1)
and S403 (domain 2) are noted. ADP·BeF[3] and 
are
shown with sticks and color coded.