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Figure 1.
Overall structure of MjPSTK. (A) Ribbon representation of the
crystal structure of the MjPSTK dimer, consisting of the
N-terminal domain (residues 3–177, blue) and the C-terminal
domain (188–231 and 237–252, orange). The AMPPNP molecule is
shown as a ball-and-stick model. (B) Surface representations of
PSTK (left), rotated 90° (right), consisting of the core
region (residues 3–39, 52–117, and 126–177, blue), the
A76-binding region (40–51, green) the lid region (118–125,
yellow), and the C-terminal domain (188–231 and 237–252,
orange), with the active site colored pink. The
solvent-accessible surface was calculated with the program MSMS
(26). The AMPPNP molecule is shown as a ball-and-stick model.
The white and black arrows show the width and the depth,
respectively, of the tRNA binding groove.
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