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Figure 1.
Tertiary structure of HIV-1 protease determined by neutron
diffraction. The HIV protease dimer is shown by a ball and stick
model; water molecules and bound inhibitor are shown by
space-filling representation. Hydrogen and deuterium atoms are
colored gray. Carbon (green), oxygen (red), nitrogen (blue), and
sulfur (yellow) atoms in protease are indicated. Carbon atoms in
KNI-272 are colored dark gray. Figs. 1, 2, and 4 were made by
using the program Pymol (www.pymol.org).
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