Figure 1 - full size

 

Figure 1.
Peptide conformations within the antigen-binding cleft. CDC25b (A), IRS2 (B), β-catenin (C), CDC25b-phospho (D), IRS2-phospho (E), and β-catenin–phospho (F). Blue mesh indicates unbiased 2Fo-Fc maps contoured at 1σ. Yellow indicates nonphosphorylated peptides. Green indicates phosphorylated peptides. The bound peptide is shown from a side-on view with the α2-helix removed for clarity.