Figure 1.
Figure 1. (A) Ribbon representation of human OSF (chain B,
crystal form II). Standard numbering of the secondary elements
is indicated. (B) Ribbon representation of human OSF in two
crystal forms with SH3 domain aligned only. (Magenta for crystal
form I, green for crystal form II.) (C) Sequence alignment of
OSF SH3 domain with some other SH3 domains. Secondary structural
elements of human OSF-SH3 were shown above the alignment and Abl
SH3 domain secondary structural elements were shown below.
Conserved residues involving peptide binding are marked by *
.
(D) Structure-based sequence alignment of OSF ankyrin repeats
domain with some other ankyrin repeats. Secondary structural
elements of human OSF ankyrin repeats were shown above the
alignment. Numbers above the sequences correspond to the OSF
sequence.
The above figure is reprinted
by permission from John Wiley & Sons, Inc.:
Proteins
(2009,
75,
245-251)
copyright 2009.
*
.
(D) Structure-based sequence alignment of OSF ankyrin repeats
domain with some other ankyrin repeats. Secondary structural
elements of human OSF ankyrin repeats were shown above the
alignment. Numbers above the sequences correspond to the OSF
sequence.